Reaction Details Report a problem with these data
Target
Gastrin-releasing peptide
Ligand
BDBM50071745
Substrate
n/a
Ki
97±n/a nM
Comments
PDSP_1339
Citation
 Mantey, SA; Coy, DH; Entsuah, LK; Jensen, RT Development of bombesin analogs with conformationally restricted amino acid substitutions with enhanced selectivity for the orphan receptor human bombesin receptor subtype 3. J Pharmacol Exp Ther 310:1161-70 (2004) [PubMed]  Article 
Target
Name:
Gastrin-releasing peptide
Synonyms:
GRP | GRP_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16223.81
Organism:
Homo sapiens (Human)
Description:
Gastrin-Releasing peptide 0 HUMAN::P07492
Residue:
148
Sequence:
MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ
  
Inhibitor
Name:
BDBM50071745
Synonyms:
CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2(Neuromedin B) | NMB
Type:
Small organic molecule
Emp. Form.:
C52H73N15O12S
Mol. Mass.:
1132.294
SMILES:
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CN)[C@@H](C)O)C(N)=O
Structure:
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