Reaction Details Report a problem with these data
Target
cAMP specific phosphodiesterase variant PDE4A-10
Ligand
BDBM86639
Substrate
n/a
Meas. Tech.
In Vitro Enzyme Assay
IC50
7.0e+4±n/a nM
Citation
 Ceyhan, O; Birsoy, K; Hoffman, CS Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol 19:155-63 (2012) [PubMed]  Article 
Target
Name:
cAMP specific phosphodiesterase variant PDE4A-10
Synonyms:
Phosphodiesterase 4A10
Type:
Protein
Mol. Mass.:
4891.49
Organism:
Homo sapiens (Human)
Description:
Q9HC30
Residue:
45
Sequence:
MRSGAAPRARPRPPALALPPTGPESLTHFPFSDEDTRRHPPGRSV
  
Inhibitor
Name:
BDBM86639
Synonyms:
BC11-15 | US9173884, BC11-15
Type:
n/a
Emp. Form.:
C23H24N4OS
Mol. Mass.:
404.528
SMILES:
CCN(CC)C(=O)c1cc(nc2n(nc(C)c12)-c1ccccc1C)-c1cccs1
Structure:
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