Reaction Details Report a problem with these data
Target
GTP-binding nuclear protein GSP1/CNR1
Ligand
BDBM87014
Substrate
n/a
Ki
141±n/a nM
Comments
PDSP_8601
Citation
 Wang, H; Duffy, RA; Boykow, GC; Chackalamannil, S; Madison, VS Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. J Med Chem 51:2439-46 (2008) [PubMed]  Article 
Target
Name:
GTP-binding nuclear protein GSP1/CNR1
Synonyms:
CANNABINOID CB1 | CNR1 | CST17 | GSP1 | GSP1_YEAST | GTP-binding nuclear protein GSP1/CNR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24810.06
Organism:
Saccharomyces cerevisiae
Description:
CANNABINOID CB1 CNR1 0::P32835
Residue:
219
Sequence:
MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL
  
Inhibitor
Name:
BDBM87014
Synonyms:
4-(6-methoxy-2-(4-methoxyphenyl)benzofuran-3-carbonyl)benzonitrile | CAS_5311257 | NSC_5311257
Type:
Small organic molecule
Emp. Form.:
C24H17NO4
Mol. Mass.:
383.3961
SMILES:
COc1ccc(cc1)-c1oc2cc(OC)ccc2c1C(=O)c1ccc(cc1)C#N
Structure:
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