Reaction Details Report a problem with these data
Target
Polyadenylate-binding protein 1
Ligand
BDBM38028
Substrate
n/a
Meas. Tech.
Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide
IC50
>66000±n/a nM
Citation
 PubChem, PC Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide PubChem Bioassay (2012)[AID] 
Target
Name:
Polyadenylate-binding protein 1
Synonyms:
PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70694.26
Organism:
Homo sapiens (Human)
Description:
gi_46367787
Residue:
636
Sequence:
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
  
Inhibitor
Name:
BDBM38028
Synonyms:
(2-anilino-2-oxoethyl) 3-(2-oxo-1,3-dihydroimidazol-4-yl)propanoate | (2-oxidanylidene-2-phenylazanyl-ethyl) 3-(2-oxidanylidene-1,3-dihydroimidazol-4-yl)propanoate | 3-(2-Oxo-2,3-dihydro-1H-imidazol-4-yl)-propionic acid phenylcarbamoylmethyl ester | 3-(2-keto-4-imidazolin-4-yl)propionic acid (2-anilino-2-keto-ethyl) ester | 3-(2-oxo-1,3-dihydroimidazol-4-yl)propanoic acid (2-anilino-2-oxoethyl) ester | MLS000075043 | SMR000014183 | cid_655712
Type:
Small organic molecule
Emp. Form.:
C14H15N3O4
Mol. Mass.:
289.2866
SMILES:
O=C(COC(=O)CCc1c[nH]c(=O)[nH]1)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: