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Target
Polyadenylate-binding protein 1
Ligand
BDBM87624
Substrate
n/a
Meas. Tech.
Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide
IC50
>66000±n/a nM
Citation
 PubChem, PC Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide PubChem Bioassay (2012)[AID] 
Target
Name:
Polyadenylate-binding protein 1
Synonyms:
PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70694.26
Organism:
Homo sapiens (Human)
Description:
gi_46367787
Residue:
636
Sequence:
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
  
Inhibitor
Name:
BDBM87624
Synonyms:
MLS000071535 | N-[2-(benzenesulfonamido)-4-methyl-5-thiazolyl]carbamic acid propan-2-yl ester | N-[2-(benzenesulfonamido)-4-methyl-thiazol-5-yl]carbamic acid isopropyl ester | SMR000057887 | cid_660021 | propan-2-yl N-[2-(benzenesulfonamido)-4-methyl-1,3-thiazol-5-yl]carbamate | propan-2-yl N-[4-methyl-2-(phenylsulfonylamino)-1,3-thiazol-5-yl]carbamate
Type:
Small organic molecule
Emp. Form.:
C14H17N3O4S2
Mol. Mass.:
355.432
SMILES:
CC(C)OC(=O)Nc1sc(NS(=O)(=O)c2ccccc2)nc1C
Structure:
Search PDB for entries with ligand similarity: