Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM55415
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
24220±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM55415
Synonyms:
MLS000519756 | N-cyclohexyl-1-[2-furanylmethyl-(1-oxo-2-thiophen-2-ylethyl)amino]-1-cyclohexanecarboxamide | N-cyclohexyl-1-[2-furfuryl-[2-(2-thienyl)acetyl]amino]cyclohexanecarboxamide | N-cyclohexyl-1-[furan-2-ylmethyl(2-thiophen-2-ylethanoyl)amino]cyclohexane-1-carboxamide | N-cyclohexyl-1-[furan-2-ylmethyl-(2-thiophen-2-ylacetyl)amino]cyclohexane-1-carboxamide | SMR000130174 | cid_4309872
Type:
Small organic molecule
Emp. Form.:
C24H32N2O3S
Mol. Mass.:
428.587
SMILES:
O=C(Cc1cccs1)N(Cc1ccco1)C1(CCCCC1)C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: