Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89072
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
660±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89072
Synonyms:
MLS-0454741.0001 | [(Z)-[amino-(2,2-dimethylchromen-6-yl)methylidene]amino] benzoate | [(Z)-[azanyl-(2,2-dimethylchromen-6-yl)methylidene]amino] benzoate | benzoic acid [(Z)-[amino-(2,2-dimethyl-1-benzopyran-6-yl)methylidene]amino] ester | benzoic acid [(Z)-[amino-(2,2-dimethylchromen-6-yl)methylene]amino] ester | cid_9584415
Type:
Small organic molecule
Emp. Form.:
C19H18N2O3
Mol. Mass.:
322.3578
SMILES:
CC1(C)Oc2ccc(cc2C=C1)C(=N)NOC(=O)c1ccccc1 |c:11|
Structure:
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