Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89055
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
24940±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89055
Synonyms:
2-(2,4-dichlorophenoxy)acetic acid [(Z)-[1-amino-2-(1-naphthalenyl)ethylidene]amino] ester | 2-(2,4-dichlorophenoxy)acetic acid [(Z)-[1-amino-2-(1-naphthyl)ethylidene]amino] ester | MLS-0454724.0001 | [(Z)-(1-amino-2-naphthalen-1-ylethylidene)amino] 2-(2,4-dichlorophenoxy)acetate | [(Z)-(1-azanyl-2-naphthalen-1-yl-ethylidene)amino] 2-[2,4-bis(chloranyl)phenoxy]ethanoate | cid_9660592
Type:
Small organic molecule
Emp. Form.:
C20H16Cl2N2O3
Mol. Mass.:
403.259
SMILES:
Clc1ccc(OCC(=O)ONC(=N)Cc2cccc3ccccc23)c(Cl)c1
Structure:
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