Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89063
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
15600±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89063
Synonyms:
3,4-dichlorobenzoic acid [(Z)-[amino-[3-(2-pyridinylsulfonylmethyl)phenyl]methylidene]amino] ester | 3,4-dichlorobenzoic acid [(Z)-[amino-[3-(2-pyridylsulfonylmethyl)phenyl]methylene]amino] ester | MLS-0454732.0001 | [(Z)-[amino-[3-(pyridin-2-ylsulfonylmethyl)phenyl]methylidene]amino] 3,4-dichlorobenzoate | [(Z)-[azanyl-[3-(pyridin-2-ylsulfonylmethyl)phenyl]methylidene]amino] 3,4-bis(chloranyl)benzoate | cid_9584197
Type:
Small organic molecule
Emp. Form.:
C20H15Cl2N3O4S
Mol. Mass.:
464.322
SMILES:
Clc1ccc(cc1Cl)C(=O)ONC(=N)c1cccc(CS(=O)(=O)c2ccccn2)c1
Structure:
Search PDB for entries with ligand similarity: