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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90013
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90013
Synonyms:
(2,4-dichlorophenyl)methyl N-(5-chloranyl-1,3-dimethyl-pyrazol-4-yl)carbamate | (2,4-dichlorophenyl)methyl N-(5-chloro-1,3-dimethylpyrazol-4-yl)carbamate | 2,4-dichlorobenzyl N-(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)carbamate | MLS000547376 | N-(5-chloro-1,3-dimethyl-4-pyrazolyl)carbamic acid (2,4-dichlorophenyl)methyl ester | N-(5-chloro-1,3-dimethyl-pyrazol-4-yl)carbamic acid (2,4-dichlorobenzyl) ester | SMR000180275 | cid_3323365
Type:
Small organic molecule
Emp. Form.:
C13H12Cl3N3O2
Mol. Mass.:
348.612
SMILES:
Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl
Structure:
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