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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM91331
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM91331
Synonyms:
MLS002252515 | N'-(phenylcarbonyl)-3-piperidin-1-ylsulfonyl-benzohydrazide | N'-benzoyl-3-(1-piperidinylsulfonyl)benzohydrazide | N'-benzoyl-3-piperidin-1-ylsulfonylbenzohydrazide | N'-benzoyl-3-piperidinosulfonyl-benzohydrazide | SMR001314857 | cid_2445760
Type:
Small organic molecule
Emp. Form.:
C19H21N3O4S
Mol. Mass.:
387.453
SMILES:
O=C(NNC(=O)c1cccc(c1)S(=O)(=O)N1CCCCC1)c1ccccc1
Structure:
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