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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM88741
Substrate
n/a
Meas. Tech.
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50
24100±n/a nM
Citation
 PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM88741
Synonyms:
5-bromanyl-N-[(E)-(4-bromophenyl)methylideneamino]furan-2-carboxamide | 5-bromo-N'-(4-bromobenzylidene)-2-furohydrazide | 5-bromo-N-[(E)-(4-bromobenzylidene)amino]-2-furamide | 5-bromo-N-[(E)-(4-bromophenyl)methylideneamino]-2-furancarboxamide | 5-bromo-N-[(E)-(4-bromophenyl)methylideneamino]furan-2-carboxamide | MLS000701675 | SMR000227123 | cid_9564721
Type:
Small organic molecule
Emp. Form.:
C12H8Br2N2O2
Mol. Mass.:
372.012
SMILES:
Brc1ccc(o1)C(=O)N\N=C\c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: