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Target
Mitogen-activated protein kinase 1
Ligand
BDBM91996
Substrate
n/a
Meas. Tech.
Assay 1
Ki
1000±n/a nM
Citation
 CSARdock, CD ERK2 in CSAR_FULL_RELEASE_3JULY2012 CSAR 1:0 (2012)  
Target
Name:
Mitogen-activated protein kinase 1
Synonyms:
ERK2 | ERT1 | Extracellular signal-regulated kinase 2 | Extracellular signal-regulated kinase 2 (ERK-2) | Extracellular signal-regulated kinase 2 (ERK2) | MAP Kinase 2/ERK2 | MAPK 2 | MAPK1 | MK01_HUMAN | Mitogen activated kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK-2) | Mitogen-activated protein kinase 1 (ERK2) | Mitogen-activated protein kinase 2 | PRKM1 | PRKM2 | p42-MAPK
Type:
Ser/Thr Protein Kinase
Mol. Mass.:
41392.76
Organism:
Homo sapiens (Human)
Description:
P28482
Residue:
360
Sequence:
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
  
Inhibitor
Name:
BDBM91996
Synonyms:
erk000075
Type:
n/a
Emp. Form.:
C20H22N4O2
Mol. Mass.:
350.4143
SMILES:
Cc1onc(c1-c1ccnc(NC2CCC(O)CC2)n1)-c1ccccc1 |(1.33,-.77,;1.33,-2.31,;2.58,-3.22,;2.1,-4.68,;.56,-4.68,;.09,-3.22,;-1.38,-2.74,;-1.7,-1.23,;-3.16,-.76,;-4.31,-1.79,;-3.99,-3.29,;-5.13,-4.32,;-6.59,-3.85,;-7.74,-4.88,;-9.2,-4.4,;-9.52,-2.9,;-10.99,-2.42,;-8.38,-1.87,;-6.92,-2.34,;-2.52,-3.77,;-.34,-5.93,;.28,-7.33,;-.62,-8.58,;-2.15,-8.42,;-2.78,-7.01,;-1.87,-5.76,)|
Structure:
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