Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM92409
Substrate
n/a
Meas. Tech.
Tautomerase Activity Assay
IC50
9.5e+3± 1.7e+3 nM
Citation
 Alam, A; Haldar, S; Thulasiram, HV; Kumar, R; Goyal, M; Iqbal, MS; Pal, C; Dey, S; Bindu, S; Sarkar, S; Pal, U; Maiti, NC; Bandyopadhyay, U Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor: INHIBITION OF TAUTOMERASE AND PROINFLAMMATORY ACTIVITIES OF MACROPHAGE MIGRATION INHIBITORY FACTOR. J Biol Chem 287:24844-61 (2012) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
Macrophage migration inhibitory factor (MIF)
Type:
Enzyme
Mol. Mass.:
12844.38
Organism:
Plasmodium falciparum
Description:
Q6Q3H7
Residue:
116
Sequence:
MPCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSIGGINRSNNSALADQITKLLVSNLNVKSRRIYVEFRDCSAQNFAFSGSLFG
  
Inhibitor
Name:
BDBM92409
Synonyms:
Epoxyazadiradione
Type:
Small organic molecule
Emp. Form.:
C28H34O6
Mol. Mass.:
466.566
SMILES:
CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1 |c:12|
Structure:
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