Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM92411
Substrate
n/a
Meas. Tech.
Tautomerase Activity Assay
IC50
8.95e+4± 6.9e+3 nM
Citation
 Alam, A; Haldar, S; Thulasiram, HV; Kumar, R; Goyal, M; Iqbal, MS; Pal, C; Dey, S; Bindu, S; Sarkar, S; Pal, U; Maiti, NC; Bandyopadhyay, U Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor: INHIBITION OF TAUTOMERASE AND PROINFLAMMATORY ACTIVITIES OF MACROPHAGE MIGRATION INHIBITORY FACTOR. J Biol Chem 287:24844-61 (2012) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
Macrophage migration inhibitory factor (MIF)
Type:
Enzyme
Mol. Mass.:
12844.38
Organism:
Plasmodium falciparum
Description:
Q6Q3H7
Residue:
116
Sequence:
MPCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSIGGINRSNNSALADQITKLLVSNLNVKSRRIYVEFRDCSAQNFAFSGSLFG
  
Inhibitor
Name:
BDBM92411
Synonyms:
Salannin
Type:
Small organic molecule
Emp. Form.:
C34H44O9
Mol. Mass.:
596.7078
SMILES:
COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@@H]2OC[C@@]3(C)[C@H]2[C@]1(C)[C@H](C[C@H]3OC(C)=O)OC(=O)C(\C)=C\C |r,t:14|
Structure:
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