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Target
Prolyl 4-hydroxylase subunit alpha-1
Ligand
BDBM50336491
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
>20000000±0.0 nM
Citation
 Majamaa, K; Günzler, V; Hanauske-Abel, HM; Myllylä, R; Kivirikko, KI Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem 261:7819-23 (1986) [PubMed] 
Target
Name:
Prolyl 4-hydroxylase subunit alpha-1
Synonyms:
P4HA | P4HA1 | P4HA1_CHICK | Procollagen-proline,2-oxoglutarate-4-dioxygenase | Prolyl 4-hydroxylase subunit alpha-1
Type:
Protein
Mol. Mass.:
59433.79
Organism:
Gallus gallus (Chicken)
Description:
P16924
Residue:
516
Sequence:
HTDFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGELESLVLKDMSDGFISNMTIQRQFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLPERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRYILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
  
Inhibitor
Name:
BDBM50336491
Synonyms:
3-Hydroxy-benzoic acid | 3-Hydroxybenzoate | 3-Hydroxybenzoate, II | 3-hydroxybenzoic acid | CHEMBL65369
Type:
Small organic molecule
Emp. Form.:
C7H6O3
Mol. Mass.:
138.1207
SMILES:
OC(=O)c1cccc(O)c1
Structure:
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