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Target
Prolyl 4-hydroxylase subunit alpha-1
Ligand
BDBM26188
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
25000±0.0 nM
Citation
 Majamaa, K; Günzler, V; Hanauske-Abel, HM; Myllylä, R; Kivirikko, KI Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem 261:7819-23 (1986) [PubMed] 
Target
Name:
Prolyl 4-hydroxylase subunit alpha-1
Synonyms:
P4HA | P4HA1 | P4HA1_CHICK | Procollagen-proline,2-oxoglutarate-4-dioxygenase | Prolyl 4-hydroxylase subunit alpha-1
Type:
Protein
Mol. Mass.:
59433.79
Organism:
Gallus gallus (Chicken)
Description:
P16924
Residue:
516
Sequence:
HTDFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGELESLVLKDMSDGFISNMTIQRQFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLPERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRYILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
  
Inhibitor
Name:
BDBM26188
Synonyms:
α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI | 1,2-dihydroxybenzene | CHEMBL280998 | benzene-1,2-diol | phenol derivative, 2
Type:
Small organic molecule
Emp. Form.:
C6H6O2
Mol. Mass.:
110.1106
SMILES:
Oc1ccccc1O
Structure:
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