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Target
Prolyl 4-hydroxylase subunit alpha-1
Ligand
BDBM52946
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
9000±0.0 nM
Citation
 Majamaa, K; Günzler, V; Hanauske-Abel, HM; Myllylä, R; Kivirikko, KI Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem 261:7819-23 (1986) [PubMed] 
Target
Name:
Prolyl 4-hydroxylase subunit alpha-1
Synonyms:
P4HA | P4HA1 | P4HA1_CHICK | Procollagen-proline,2-oxoglutarate-4-dioxygenase | Prolyl 4-hydroxylase subunit alpha-1
Type:
Protein
Mol. Mass.:
59433.79
Organism:
Gallus gallus (Chicken)
Description:
P16924
Residue:
516
Sequence:
HTDFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGELESLVLKDMSDGFISNMTIQRQFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLPERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRYILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
  
Inhibitor
Name:
BDBM52946
Synonyms:
2-(3,4-dihydroxyphenyl)acetic acid | 2-[3,4-bis(oxidanyl)phenyl]ethanoic acid | 3,4-Dihydroxyphenylacetate, XV | 3,4-Dihydroxyphenylacetic acid | MLS001056737 | SMR000326727 | cid_547
Type:
Small organic molecule
Emp. Form.:
C8H8O4
Mol. Mass.:
168.1467
SMILES:
OC(=O)Cc1ccc(O)c(O)c1
Structure:
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