Reaction Details Report a problem with these data
Target
Isochorismatase family protein
Ligand
BDBM23515
Substrate
n/a
Meas. Tech.
GDH-Coupled Nicotinamidase Assay
Ki
2000000±0 nM
Citation
 French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry 49:10421-39 (2010) [PubMed]  Article 
Target
Name:
Isochorismatase family protein
Synonyms:
Nicotinamidase (SpNic) | Pyrazinamidase/nicotinamidase
Type:
Enzyme
Mol. Mass.:
21361.69
Organism:
Streptococcus pneumoniae
Description:
A0A098ZGI7
Residue:
191
Sequence:
MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFERGDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMDKRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVASIWPENHQFALGHFKNTLGAKLVDENLNELSE
  
Inhibitor
Name:
BDBM23515
Synonyms:
CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-niacin | pyridine-3-carboxylic acid | wampocap
Type:
Small organic molecule
Emp. Form.:
C6H5NO2
Mol. Mass.:
123.1094
SMILES:
OC(=O)c1cccnc1
Structure:
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