Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM93159
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
>1000±0.0 nM
Citation
 Yous, S; Wallez, V; Belloir, M; Caignard, DH; McCurdy, CR; Poupaert, JH Novel 2(3H)-benzothiazolones as highly potent and selective sigma-1 receptor ligands Medicinal Chemistry Research 14:158-168 (2005)    Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM93159
Synonyms:
1-(2-chloroethyl)piperidine, 19
Type:
Small molecule
Emp. Form.:
C18H22N2O2S
Mol. Mass.:
330.444
SMILES:
O=C(C1CC1)c1ccc2n(CCN3CCCCC3)c(=O)sc2c1
Structure:
Search PDB for entries with ligand similarity: