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Target
Beta-lactamase
Ligand
BDBM66519
Substrate
n/a
IC50
21302±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM66519
Synonyms:
(5E)-3-(3-chlorophenyl)-5-[(5-morpholin-4-ylfuran-2-yl)methylidene]imidazolidine-2,4-dione | (5E)-3-(3-chlorophenyl)-5-[(5-morpholino-2-furyl)methylene]hydantoin | (5E)-3-(3-chlorophenyl)-5-[[5-(4-morpholinyl)-2-furanyl]methylidene]imidazolidine-2,4-dione | 3-(3-chlorophenyl)-5-{[5-(4-morpholinyl)-2-furyl]methylene}-2,4-imidazolidinedione | MLS000663854 | SMR000292374 | cid_1782242
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O4
Mol. Mass.:
373.79
SMILES:
Clc1cccc(c1)N1C(=O)NC(=Cc2ccc(o2)N2CCOCC2)C1=O |w:12.13|
Structure:
Search PDB for entries with ligand similarity: