Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM93480
Substrate
n/a
IC50
19442±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM93480
Synonyms:
1-hydroxy-2-methyl-N-phenyl-6-(trifluoromethyl)-1H-indole-3-carboxamide | 1-hydroxy-2-methyl-N-phenyl-6-(trifluoromethyl)-3-indolecarboxamide | 1-hydroxy-2-methyl-N-phenyl-6-(trifluoromethyl)indole-3-carboxamide | 2-methyl-1-oxidanyl-N-phenyl-6-(trifluoromethyl)indole-3-carboxamide | MLS001181026 | SMR000476440 | cid_901336
Type:
Small organic molecule
Emp. Form.:
C17H13F3N2O2
Mol. Mass.:
334.2925
SMILES:
Cc1c(C(=O)Nc2ccccc2)c2ccc(cc2n1O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: