Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM60974
Substrate
n/a
IC50
14096±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM60974
Synonyms:
MLS001291206 | N-(3-maleimidophenyl)thiophene-2-carboxamide | N-[3-(2,5-dioxo-1-pyrrolyl)phenyl]-2-thiophenecarboxamide | N-[3-(2,5-dioxopyrrol-1-yl)phenyl]thiophene-2-carboxamide | N-[3-[2,5-bis(oxidanylidene)pyrrol-1-yl]phenyl]thiophene-2-carboxamide | SMR000611660 | Thiophene-2-carboxylic acid [3-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-phenyl]-amide | cid_881135
Type:
Small organic molecule
Emp. Form.:
C15H10N2O3S
Mol. Mass.:
298.316
SMILES:
O=C(Nc1cccc(c1)N1C(=O)C=CC1=O)c1cccs1 |c:13|
Structure:
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