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Target
Beta-lactamase
Ligand
BDBM93524
Substrate
n/a
IC50
20003±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM93524
Synonyms:
MLS003124149 | N-[2-(dimethylamino)ethyl]-3-[6-(4-ethylsulfanylphenyl)-8-formamido-imidazo[1,2-a]pyridin-3-yl]benzamide | N-[2-(dimethylamino)ethyl]-3-[6-(4-ethylsulfanylphenyl)-8-formamidoimidazo[1,2-a]pyridin-3-yl]benzamide | N-[2-(dimethylamino)ethyl]-3-[6-[4-(ethylthio)phenyl]-8-formamido-3-imidazo[1,2-a]pyridinyl]benzamide | N-[2-(dimethylamino)ethyl]-3-[6-[4-(ethylthio)phenyl]-8-formamido-imidazo[1,2-a]pyridin-3-yl]benzamide | SMR001292619 | cid_46944084
Type:
Small organic molecule
Emp. Form.:
C27H29N5O2S
Mol. Mass.:
487.616
SMILES:
CCSc1ccc(cc1)-c1cc(NC=O)c2ncc(-c3cccc(c3)C(=O)NCCN(C)C)n2c1
Structure:
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