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Target
Sentrin-specific protease 8
Ligand
BDBM93611
Substrate
n/a
IC50
2350±263 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM93611
Synonyms:
(4-chloro-3-nitro-phenyl)-[(5-nitro-2-thienyl)methylene]amine | 4-chloro-3-nitro-N-[(5-nitro-2-thienyl)methylene]aniline | MLS000702279 | N-(4-chloranyl-3-nitro-phenyl)-1-(5-nitrothiophen-2-yl)methanimine | N-(4-chloro-3-nitrophenyl)-1-(5-nitro-2-thiophenyl)methanimine | N-(4-chloro-3-nitrophenyl)-1-(5-nitrothiophen-2-yl)methanimine | SMR000228570 | cid_628390
Type:
Small organic molecule
Emp. Form.:
C11H6ClN3O4S
Mol. Mass.:
311.701
SMILES:
[O-][N+](=O)c1ccc(\C=N\c2ccc(Cl)c(c2)[N+]([O-])=O)s1
Structure:
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