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Target
Sentrin-specific protease 8
Ligand
BDBM93626
Substrate
n/a
IC50
1010±94 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM93626
Synonyms:
1-methyl-8-quinolin-1-iumolate;hydrate | 1-methylquinolin-1-ium-8-olate;hydrate | MLS000767219 | SMR000429550 | cid_16682476
Type:
Small organic molecule
Emp. Form.:
C10H9NO
Mol. Mass.:
159.1846
SMILES:
C[n+]1cccc2cccc([O-])c12
Structure:
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