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Target
Sentrin-specific protease 8
Ligand
BDBM38843
Substrate
n/a
IC50
2140±172 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM38843
Synonyms:
(3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolinamine | 3-methylcinnolin-5-amine | MLS000105193 | SMR000055122 | cid_5310645
Type:
Small organic molecule
Emp. Form.:
C9H9N3
Mol. Mass.:
159.1879
SMILES:
Cc1cc2c(N)cccc2nn1
Structure:
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