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Target
Sentrin-specific protease 8
Ligand
BDBM93638
Substrate
n/a
IC50
2470±227 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM93638
Synonyms:
4-[(5-nitro-2-thienyl)methyleneamino]benzamide | 4-[(5-nitro-2-thiophenyl)methylideneamino]benzamide | 4-[(5-nitrothiophen-2-yl)methylideneamino]benzamide | 4-{[(5-nitro-2-thienyl)methylene]amino}benzamide | MLS000595175 | SMR000184916 | cid_623812
Type:
Small organic molecule
Emp. Form.:
C12H9N3O3S
Mol. Mass.:
275.283
SMILES:
NC(=O)c1ccc(cc1)\N=C\c1ccc(s1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: