Reaction Details Report a problem with these data
Target
Protein Wnt-3a
Ligand
BDBM89372
Substrate
n/a
IC50
369±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM89372
Synonyms:
1-(4-bromobenzyl)-2-methyl-1H-benzimidazole | 1-(4-bromobenzyl)-2-methyl-benzimidazole | 1-[(4-bromophenyl)methyl]-2-methyl-benzimidazole | 1-[(4-bromophenyl)methyl]-2-methylbenzimidazole | MLS001077238 | SMR000473021 | cid_743662
Type:
Small organic molecule
Emp. Form.:
C15H13BrN2
Mol. Mass.:
301.181
SMILES:
Cc1nc2ccccc2n1Cc1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: