Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93714
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93714
Synonyms:
Furan-2-carboxylic acid naphtho[1,2-d]thiazol-2-ylamide | MLS000084989 | N-(2-benzo[e][1,3]benzothiazolyl)-2-furancarboxamide | N-benzo[e][1,3]benzothiazol-2-yl-2-furamide | N-benzo[e][1,3]benzothiazol-2-ylfuran-2-carboxamide | SMR000019335 | cid_565816
Type:
Small organic molecule
Emp. Form.:
C16H10N2O2S
Mol. Mass.:
294.328
SMILES:
O=C(Nc1nc2c(ccc3ccccc23)s1)c1ccco1
Structure:
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