Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM94553
Substrate
n/a
IC50
1817±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM94553
Synonyms:
(2,2,4-trimethyl-1H-quinolin-6-yl) 2-(1,3-dioxoisoindol-2-yl)propanoate | (2,2,4-trimethyl-1H-quinolin-6-yl) 2-[1,3-bis(oxidanylidene)isoindol-2-yl]propanoate | 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propionic acid 2,2,4-trimethyl-1,2-dihydro-quinolin-6-yl ester | 2-(1,3-dioxo-2-isoindolyl)propanoic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester | 2-phthalimidopropionic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester | MLS000563332 | SMR000176589 | cid_2874907
Type:
Small organic molecule
Emp. Form.:
C23H22N2O4
Mol. Mass.:
390.4318
SMILES:
CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc1ccc2NC(C)(C)C=C(C)c2c1 |t:26|
Structure:
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