Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM48194
Substrate
n/a
IC50
1722±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM48194
Synonyms:
(2,2,4-trimethyl-1H-quinolin-6-yl) 2-(2,5-dioxopyrrolidin-1-yl)acetate | (2,2,4-trimethyl-1H-quinolin-6-yl) 2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethanoate | 2-(2,5-dioxo-1-pyrrolidinyl)acetic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester | 2-succinimidoacetic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester | MLS000107719 | SMR000103684 | cid_1749332
Type:
Small organic molecule
Emp. Form.:
C18H20N2O4
Mol. Mass.:
328.3624
SMILES:
CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)CCC3=O)cc12 |t:1|
Structure:
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