Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM37234
Substrate
n/a
IC50
1934±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM37234
Synonyms:
(2,2,4-trimethyl-1H-quinolin-6-yl) pyridine-3-carboxylate | 3-pyridinecarboxylic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester | MLS000111190 | SMR000107116 | cid_2904443 | nicotinic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester
Type:
Small organic molecule
Emp. Form.:
C18H18N2O2
Mol. Mass.:
294.3477
SMILES:
CC1=CC(C)(C)Nc2ccc(OC(=O)c3cccnc3)cc12 |t:1|
Structure:
Search PDB for entries with ligand similarity: