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Target
Perilipin-5
Ligand
BDBM94572
Substrate
n/a
IC50
6255±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM94572
Synonyms:
5-[[3-[(Z)-2-nitroethenyl]-1-indolyl]methyl]-2-furancarboxylic acid methyl ester | 5-[[3-[(Z)-2-nitrovinyl]indol-1-yl]methyl]furan-2-carboxylic acid methyl ester | MLS001007986 | SMR000498283 | cid_5741027 | methyl 5-[[3-[(Z)-2-nitroethenyl]indol-1-yl]methyl]furan-2-carboxylate | methyl 5-{[3-(2-nitrovinyl)-1H-indol-1-yl]methyl}-2-furoate
Type:
Small organic molecule
Emp. Form.:
C17H14N2O5
Mol. Mass.:
326.3035
SMILES:
COC(=O)c1ccc(Cn2cc(\C=C/[N+]([O-])=O)c3ccccc23)o1
Structure:
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