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Target
Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95173
Substrate
n/a
IC50
15700±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
  
Inhibitor
Name:
BDBM95173
Synonyms:
MLS000438847 | SMR000452599 | [3-(4-cyanophenyl)-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] cyclopentanecarboxylate | [3-(4-cyanophenyl)-7-methyl-6,8-dioxoisochromen-7-yl] cyclopentanecarboxylate | cid_16759476 | cyclopentanecarboxylic acid [3-(4-cyanophenyl)-6,8-diketo-7-methyl-isochromen-7-yl] ester | cyclopentanecarboxylic acid [3-(4-cyanophenyl)-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester
Type:
Small organic molecule
Emp. Form.:
C23H19NO5
Mol. Mass.:
389.4007
SMILES:
CC1(OC(=O)C2CCCC2)C(=O)C=C2C=C(OC=C2C1=O)c1ccc(cc1)C#N |c:15,18,t:13|
Structure:
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