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Target
Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95186
Substrate
n/a
IC50
10700±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
  
Inhibitor
Name:
BDBM95186
Synonyms:
2-Chloro-5-{5-[(naphtho[2,1-b]furan-2-carbonyl)-hydrazonomethyl]-furan-2-yl}-benzoic acid | 5-[5-[(E)-(benzo[e][1]benzofuran-2-carbonylhydrazinylidene)methyl]furan-2-yl]-2-chlorobenzoic acid | 5-[5-[(E)-(benzo[e][1]benzofuran-2-ylcarbonylhydrazinylidene)methyl]furan-2-yl]-2-chloranyl-benzoic acid | 5-[5-[(E)-(benzo[e]benzofuran-2-carbonylhydrazono)methyl]-2-furyl]-2-chloro-benzoic acid | 5-[5-[(E)-[[2-benzo[e]benzofuranyl(oxo)methyl]hydrazinylidene]methyl]-2-furanyl]-2-chlorobenzoic acid | MLS001043284 | SMR000415050 | cid_6884195
Type:
Small organic molecule
Emp. Form.:
C25H15ClN2O5
Mol. Mass.:
458.85
SMILES:
OC(=O)c1cc(ccc1Cl)-c1ccc(\C=N\NC(=O)c2cc3c(ccc4ccccc34)o2)o1
Structure:
Search PDB for entries with ligand similarity: