Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95187
Substrate
n/a
IC50
12000±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM95187
Synonyms:
2-Amino-benzoic acid N'-((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoyl)-hydrazide | 2-amino-N'-[(Z)-4-hydroxy-1,2-dioxo-4-phenylbut-3-enyl]benzohydrazide | 2-amino-N'-[(Z)-4-hydroxy-2-keto-4-phenyl-but-3-enoyl]benzohydrazide | 2-amino-N'-[(Z)-4-hydroxy-2-oxo-4-phenylbut-3-enoyl]benzohydrazide | 2-azanyl-N'-[(Z)-4-oxidanyl-2-oxidanylidene-4-phenyl-but-3-enoyl]benzohydrazide | MLS001075302 | SMR000427706 | cid_5600863
Type:
Small organic molecule
Emp. Form.:
C17H15N3O4
Mol. Mass.:
325.3187
SMILES:
Nc1ccccc1C(=O)NNC(=O)C(=O)CC(=O)c1ccccc1
Structure:
