Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95385
Substrate
n/a
IC50
113841±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95385
Synonyms:
2-N,5-N-bis[(E)-furan-2-ylmethylideneamino]furan-2,5-dicarboxamide | MLS000702587 | N'~2~,N'~5~-bis(2-furylmethylene)-2,5-furandicarbohydrazide | N,N'-bis[(E)-2-furfurylideneamino]furan-2,5-dicarboxamide | N2,N5-bis[(E)-2-furanylmethylideneamino]furan-2,5-dicarboxamide | N2,N5-bis[(E)-furan-2-ylmethylideneamino]furan-2,5-dicarboxamide | SMR000227616 | cid_6874196
Type:
Small organic molecule
Emp. Form.:
C16H12N4O5
Mol. Mass.:
340.2903
SMILES:
O=C(N\N=C\c1ccco1)c1ccc(o1)C(=O)N\N=C\c1ccco1
Structure:
Search PDB for entries with ligand similarity: