Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95419
Substrate
n/a
IC50
102831±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95419
Synonyms:
(4-{2-[2-(benzoylamino)-5-phenyl-2,4-pentadienoyl]carbonohydrazonoyl}phenoxy)acetic acid | 2-[4-[(E)-[[(2Z,4E)-2-benzamido-1-oxo-5-phenylpenta-2,4-dienyl]hydrazinylidene]methyl]phenoxy]acetic acid | 2-[4-[(E)-[[(2Z,4E)-2-benzamido-5-phenyl-penta-2,4-dienoyl]hydrazinylidene]methyl]phenoxy]ethanoic acid | 2-[4-[(E)-[[(2Z,4E)-2-benzamido-5-phenyl-penta-2,4-dienoyl]hydrazono]methyl]phenoxy]acetic acid | 2-[4-[(E)-[[(2Z,4E)-2-benzamido-5-phenylpenta-2,4-dienoyl]hydrazinylidene]methyl]phenoxy]acetic acid | MLS001163406 | SMR000496694 | cid_5336290
Type:
Small organic molecule
Emp. Form.:
C27H23N3O5
Mol. Mass.:
469.4886
SMILES:
OC(=O)COc1ccc(\C=N\NC(=O)C(\NC(=O)c2ccccc2)=C\C=C\c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: