Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM48028
Substrate
n/a
IC50
42393±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM48028
Synonyms:
3-[[(4E)-1-keto-4-tosylimino-2-naphthyl]amino]benzoic acid | 3-[[(4E)-4-(4-methylphenyl)sulfonylimino-1-oxidanylidene-naphthalen-2-yl]amino]benzoic acid | 3-[[(4E)-4-(4-methylphenyl)sulfonylimino-1-oxo-2-naphthalenyl]amino]benzoic acid | 3-[[(4E)-4-(4-methylphenyl)sulfonylimino-1-oxonaphthalen-2-yl]amino]benzoic acid | MLS000948051 | SMR000620246 | cid_5824722
Type:
Small organic molecule
Emp. Form.:
C24H18N2O5S
Mol. Mass.:
446.475
SMILES:
Cc1ccc(cc1)S(=O)(=O)N=C1C=C(Nc2cccc(c2)C(O)=O)C(=O)c2ccccc12 |w:10.10,t:13|
Structure:
Search PDB for entries with ligand similarity: