Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95445
Substrate
n/a
IC50
118941±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95445
Synonyms:
3-[2,4-dinitro-5-(1-piperidinylamino)phenoxy]-2-ethyl-4-pyranone | 3-[2,4-dinitro-5-(piperidin-1-ylamino)phenoxy]-2-ethyl-pyran-4-one | 3-[2,4-dinitro-5-(piperidin-1-ylamino)phenoxy]-2-ethylpyran-4-one | 3-[2,4-dinitro-5-(piperidinoamino)phenoxy]-2-ethyl-pyran-4-one | MLS000949960 | SMR000462872 | cid_24792202
Type:
Small organic molecule
Emp. Form.:
C18H20N4O7
Mol. Mass.:
404.374
SMILES:
CCc1occc(=O)c1Oc1cc(NN2CCCCC2)c(cc1[N+]([O-])=O)[N+]([O-])=O
Structure:
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