Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94957
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94957
Synonyms:
(5Z)-1-[2-(4-fluorophenyl)ethyl]-5-[(piperonylamino)methylene]barbituric acid | (5Z)-5-[(1,3-benzodioxol-5-ylmethylamino)methylidene]-1-[2-(4-fluorophenyl)ethyl]-1,3-diazinane-2,4,6-trione | 5-[1-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-meth-(Z)-ylidene]-1-[2-(4-fluoro-phenyl)-ethyl]-pyrimidine-2,4, 6-trione | MLS000557507 | SMR000148423 | cid_5516744
Type:
Small organic molecule
Emp. Form.:
C21H18FN3O5
Mol. Mass.:
411.3831
SMILES:
Fc1ccc(CCN2C(=O)NC(=O)C(=CNCc3ccc4OCOc4c3)C2=O)cc1 |w:14.14|
Structure:
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