Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96807
Substrate
n/a
IC50
7946±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96807
Synonyms:
1-[2,5-dimethyl-1-(2-phenylethyl)-3-pyrrolyl]-2-[4-(1,1-dioxo-3-thiolanyl)-1-piperazinyl]ethanone | 1-[2,5-dimethyl-1-(2-phenylethyl)pyrrol-3-yl]-2-[4-(1,1-dioxothiolan-3-yl)piperazin-1-yl]ethanone | 2-[4-(1,1-diketothiolan-3-yl)piperazino]-1-(2,5-dimethyl-1-phenethyl-pyrrol-3-yl)ethanone | 2-[4-[1,1-bis(oxidanylidene)thiolan-3-yl]piperazin-1-yl]-1-[2,5-dimethyl-1-(2-phenylethyl)pyrrol-3-yl]ethanone | MLS002170213 | SMR001250534 | cid_16330350
Type:
Small organic molecule
Emp. Form.:
C24H33N3O3S
Mol. Mass.:
443.602
SMILES:
Cc1cc(C(=O)CN2CCN(CC2)C2CCS(=O)(=O)C2)c(C)n1CCc1ccccc1
Structure:
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