Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96865
Substrate
n/a
EC50
6458±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96865
Synonyms:
(2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(m-anisoylamino)-2-phenyl-acetyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3-methoxybenzoyl)amino]-2-phenylacetyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3-methoxyphenyl)carbonylamino]-2-phenyl-ethanoyl]pyrrolidine-2-carboxamide | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[[(3-methoxyphenyl)-oxomethyl]amino]-1-oxo-2-phenylethyl]-2-pyrrolidinecarboxamide | MLS003777885 | SMR002440865 | cid_53361881
Type:
Small organic molecule
Emp. Form.:
C29H30ClN3O4
Mol. Mass.:
520.019
SMILES:
COc1cccc(c1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1Cl)c1ccccc1
Structure:
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