Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96688
Substrate
n/a
IC50
>29875±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96688
Synonyms:
2-(4-phenyl-1,3-thiazol-2-yl)ethanamine;hydrochloride | 2-(4-phenyl-2-thiazolyl)ethanamine;hydrochloride | 2-(4-phenylthiazol-2-yl)ethylamine;hydrochloride | MLS000718869 | SMR000291137 | cid_16192921
Type:
Small organic molecule
Emp. Form.:
C11H12N2S
Mol. Mass.:
204.291
SMILES:
NCCc1nc(cs1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: