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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96746
Substrate
n/a
IC50
>29877±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96746
Synonyms:
2-(2-phenylethylcarbamoyl)bicyclo[2.2.1]heptane-3-carboxylic acid | 2-[oxo-(2-phenylethylamino)methyl]-3-bicyclo[2.2.1]heptanecarboxylic acid | 3-(phenethylcarbamoyl)norbornane-2-carboxylic acid | 3-{[(2-phenylethyl)amino]carbonyl}bicyclo[2.2.1]heptane-2-carboxylic acid | MLS001000987 | SMR000499205 | cid_6468911
Type:
Small organic molecule
Emp. Form.:
C17H21NO3
Mol. Mass.:
287.3535
SMILES:
[H]C12CCC([H])(C1)C(C2C(O)=O)C(=O)NCCc1ccccc1 |TLB:12:7:6:3.2,THB:9:8:6:3.2|
Structure:
Search PDB for entries with ligand similarity: