Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM90013
Substrate
n/a
IC50
2130±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM90013
Synonyms:
(2,4-dichlorophenyl)methyl N-(5-chloranyl-1,3-dimethyl-pyrazol-4-yl)carbamate | (2,4-dichlorophenyl)methyl N-(5-chloro-1,3-dimethylpyrazol-4-yl)carbamate | 2,4-dichlorobenzyl N-(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)carbamate | MLS000547376 | N-(5-chloro-1,3-dimethyl-4-pyrazolyl)carbamic acid (2,4-dichlorophenyl)methyl ester | N-(5-chloro-1,3-dimethyl-pyrazol-4-yl)carbamic acid (2,4-dichlorobenzyl) ester | SMR000180275 | cid_3323365
Type:
Small organic molecule
Emp. Form.:
C13H12Cl3N3O2
Mol. Mass.:
348.612
SMILES:
Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: