Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM88837
Substrate
n/a
IC50
>277.93±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM88837
Synonyms:
2-[(E)-2-(3-methyl-2-thienyl)vinyl]quinoline | 2-[(E)-2-(3-methyl-2-thiophenyl)ethenyl]quinoline | 2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]quinoline | MLS000565205 | SMR000152454 | cid_6056275
Type:
Small organic molecule
Emp. Form.:
C16H13NS
Mol. Mass.:
251.346
SMILES:
Cc1ccsc1\C=C\c1ccc2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: