Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM93823
Substrate
n/a
IC50
>277.73±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM93823
Synonyms:
(E)-3-(4-methylanilino)-1-thiophen-2-yl-2-propen-1-one | (E)-3-(4-methylanilino)-1-thiophen-2-ylprop-2-en-1-one | (E)-3-(p-toluidino)-1-(2-thienyl)prop-2-en-1-one | (E)-3-[(4-methylphenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one | 3-[(4-methylphenyl)amino]-1-(2-thienyl)-2-propen-1-one | MLS000671966 | SMR000294473 | cid_2210959
Type:
Small organic molecule
Emp. Form.:
C14H13NOS
Mol. Mass.:
243.324
SMILES:
Cc1ccc(cc1)N=CCC(=O)c1cccs1 |w:7.7|
Structure:
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