Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM49824
Substrate
n/a
IC50
>834.26±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM49824
Synonyms:
3-chloranyl-4-fluoranyl-N-pyridin-2-yl-1-benzothiophene-2-carboxamide | 3-chloro-4-fluoro-N-(2-pyridinyl)-1-benzothiophene-2-carboxamide | 3-chloro-4-fluoro-N-(2-pyridyl)benzothiophene-2-carboxamide | 3-chloro-4-fluoro-N-2-pyridinyl-1-benzothiophene-2-carboxamide | 3-chloro-4-fluoro-N-pyridin-2-yl-1-benzothiophene-2-carboxamide | MLS000684152 | SMR000295829 | cid_1244206
Type:
Small organic molecule
Emp. Form.:
C14H8ClFN2OS
Mol. Mass.:
306.743
SMILES:
Fc1cccc2sc(C(=O)Nc3ccccn3)c(Cl)c12
Structure:
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